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RRP ISA Survey Results
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Pulmonary RRP

Both Bettie Steinberg, PhD and Ian Frazer, MD are experts on HPV/RRP. They have indicated in private discussion with the director of RRP ISA that Gardasil might very well act prophylactically to prevent further spread of RRP/HPV to the lungs in patients already diagnosed with laryngeal or tracheal RRP.

There isn't much that can help pulmonary RRP, unfortunately. Interferon (Intron A or Alferon, nor Roferon) can perhaps slow it down. Cidofovir doesn't work and is extremely toxic when delivered systemically. We don't have enough data to say much about Gardasil and artemisinin, though that combination might (??) be useful. We have heard patient reports on the use of Tarceva, and how this seems to have slowed or resolved pulmonary RRP, but these reports are few. A world class authority on head and neck cancer, Dr. Renato Martins, verbally reported that one patient with pulmonary RRP dramatically responded to Tarceva. He said he would be publishing the findings.

See http://www.bio-medicine.org/biology-news/Combination-therapy-shows-promising-results-in-patients-with-advanced-lung-cancer-3627-1/.

Celebrex can potentiate Tarceva up to three times. This report, therefore, might have enormous applicability with respect to pulmonary RRP.